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a Cleavage of pre-rRNA, ribose methylation of 2' hydroxyl groups (2'OMe), pseudouridylation (Pseudo-U), function not yet determined (ND).
b Human homolog of yeast Gar1 has not been identified (?); fibrillarin (Fb), Th/To autoantigens.
c Despite conforming to box C/D or box H/ACA consensus structures, complementarity of U17, snR4, snR9, and snR13, snR37, snR43, snR45, to rRNA is not apparent; U3 exhibits complementarity to the 5' external transcribed spacer and 18S.
\|[Dagger]\| Ni et al., 1997 report snR10 functions in Pseudo-U while Ganot et al., 1997b report snR10 does not conform to the box H/ACA consensus structure; snR10 temperature sensitive (ts) mutation results in rRNA cleavage defects (see Maxwell and Fournier, 1995).
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